Sometimes, small changes bring unexpected benefits. A person with sore feet might buy orthopedic shoes. Suddenly, their nighttime back pain improves due to better posture. In medicine, small shifts can create similar ripple effects.

A new study shows this may be true for some vaccines. Shingrix and Arexvy protect against shingles and RSV, respectively. But they may also reduce the risk of dementia. The research, published in npj Vaccines, revealed striking results.

Both vaccines contain the immune-boosting adjuvant known as AS01. Shingrix recipients showed an 18% lower risk of dementia. Those who received Arexvy saw a 29% reduced risk. Together, the vaccines lowered dementia risk by 37%.

The results suggest dementia may not be a standalone disease. Instead, it could reflect an immune disorder within the brain. This shifts how we understand, prevent, and possibly treat dementia.

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The brain may serve as a watchtower for the immune system. It spots possible infection threats and sounds the internal alarm. As a result, the immune system may react before a virus ever enters the body.

A new study explored how the brain senses and prepares for infection. The findings show how this early response may prime immune defenses in advance.

Researchers used virtual reality to show sick avatars approaching participants. These avatars moved into participants’ peripersonal space—the area immediately near the body. The brain responded to this possible threat before any real contact happened.

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When asked about cancer risk, many think of poor lifestyle choices. People may mention alcohol, diet, lack of exercise, or even plastic exposure. But a common stomach infection may pose a far greater threat.

Helicobacter pylori (H. pylori) is a bacteria that infects the stomach lining. It spreads through contaminated food or water and often goes unnoticed. Many cases require antibiotics, though some infections resolve on their own.

A new study in Nature Medicine explored this bacterium as a hidden stomach cancer risk factor. Researchers focused on people born between 2008 and 2017 worldwide. They estimate that 15.6 million people in this group will develop gastric cancer. Of these, 11.9 million cases—or 76%—are linked to H. pylori.

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A wave of anti-vaccine sentiment continues to rise across the United States. A 2023 survey showed declining trust in established vaccines. It also found a rise in belief in vaccine misinformation, especially about COVID-19.

Despite this trend, new research highlights vaccines’ life-saving impact. A major study in published in BMJ Global Health reviewed 210 outbreaks in 49 low-income countries. These included measles, cholera, yellow fever, meningitis, and Ebola outbreaks. Researchers compared each real outbreak to a no-vaccine scenario.

The study covered outbreaks from 2000 through 2023. Models were adjusted to account for disease spread and environment. For Ebola, specific adjustments were made due to its unique features.

Across all outbreaks, vaccines prevented 5.81 million infections. This includes 4 million measles cases and 1.5 million yellow fever cases. Vaccines also saved 327,000 lives, mostly from measles and yellow fever.

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When most people imagine fungi living on human skin, they probably don’t think of anything beneficial. However, a new study from the University of Oregon found a skin yeast molecule that kills Staphylococcus aureus. S. aureus causes approximately 500,000 hospitalizations in the U.S. each year.

Caitlin Kowalski, the study’s lead researcher, says skin fungi are an untapped resource for finding new antibiotics.

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