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Please note: Due to increased travel demand, appointments are limited.

Schedule your appointment as soon as possible to ensure travel protection.

Safaris and amazing coastlines are just two reasons to visit South Africa. Travel safely with the help of Passport Health and its premier travel vaccination services.

We’ll help keep you safe at home or abroad. Book your visit online today!

Travel Vaccines and Advice for South Africa

Passport Health offers a variety of options for travelers throughout the world.
Nationwide
Travel Health
Services

Yellow fever vaccination, mosquito repellents, netting and other key vaccines can help you stay illness-free.
Yellow Fever
Vaccination
Available

See what vaccinations or medications may be recommended for your specific destination.
South Africa
Specific
Advice

Passport Health offers a variety of ways to prevent travelers' diarrhea.
Travelers’
Diarrhea Kits
Available

South Africa provides a diverse experience for travelers with a variety of landscapes and cultures.

There are nine official ethnic groups in South Africa. The largest communities include people with European, Asian and multiracial descent.

Due to this large number of different ethnicities, there are 11 official languages. This is the most official languages of any country in the world. There are also many different religions practiced throughout the country.

South Africa hold three major capital cities including Cape Town, Pretoria, and Bloemfontein.

Yes, some vaccines are recommended or required for South Africa. The CDC and WHO recommend the following vaccinations for South Africa: hepatitis A, hepatitis B, typhoid, yellow fever, rabies, meningitis, polio, measles, mumps and rubella (MMR), Tdap (tetanus, diphtheria and pertussis), chickenpox, shingles, pneumonia and influenza.

COVID-19 vaccination is recommended for travel to all regions, both foreign and domestic. Check with your local Passport Health clinic if immunization is offered in your area.

See the bullets below to learn more about some of these key immunizations:

  • COVID-19 –
    Airborne & Direct Contact –
    Recommended for all unvaccinated individuals who qualify for vaccination
  • Hepatitis A –
    Food & Water –
    Recommended for most travelers
  • Hepatitis B –
    Blood & Body Fluids –
    Accelerated schedule available
  • Typhoid –
    Food & Water –
    Shot lasts 2 years. Oral vaccine lasts 5 years, must be able to swallow pills. Oral doses must be kept in refrigerator.
  • Yellow Fever –
    Mosquito –
    Required if traveling from a country with yellow fever transmission.
  • Rabies –
    Saliva of Infected Animals –
    Vaccine recommended for certain travelers based on destination, activities and length of stay.
  • Measles Mumps Rubella (MMR) –
    Various Vectors –
    Given to anyone unvaccinated and/or born after 1957. One time adult booster recommended.
  • TDAP (Tetanus, Diphtheria & Pertussis) –
    Wounds & Airborne –
    Only one adult booster of pertussis required.
  • Chickenpox –
    Direct Contact & Airborne –
    Given to those unvaccinated that did not have chickenpox.
  • Shingles –
    Direct Contact –
    Vaccine can still be given if you have had shingles.
  • Pneumonia –
    Airborne –
    Two vaccines given separately. All 65+ or immunocompromised should receive both.
  • Influenza –
    Airborne –
    Vaccine components change annually.
  • Meningitis –
    Airborne & Direct Contact –
    Given to anyone unvaccinated or at an increased risk, especially students.
  • Polio –
    Food & Water –
    Considered a routine vaccination for most travel itineraries. Single adult booster recommended.

See the tables below for more information:

Recommended Travel Vaccinations for South Africa

VACCINE HOW DISEASE SPREADS DETAILS
COVID-19 Airborne & Direct Contact Recommended for all unvaccinated individuals who qualify for vaccination
Hepatitis A Food & Water Recommended for most travelers
Hepatitis B Blood & Body Fluids Accelerated schedule available
Typhoid Food & Water Shot lasts 2 years. Oral vaccine lasts 5 years, must be able to swallow pills. Oral doses must be kept in refrigerator.
Yellow Fever Mosquito Required if traveling from a country with yellow fever transmission.
Rabies Saliva of Infected Animals Vaccine recommended for certain travelers based on destination, activities and length of stay.

Routine Vaccinations for South Africa

VACCINE HOW DISEASE SPREADS DETAILS
Measles Mumps Rubella (MMR) Various Vectors Given to anyone unvaccinated and/or born after 1957. One time adult booster recommended.
TDAP (Tetanus, Diphtheria & Pertussis) Wounds & Airborne Only one adult booster of pertussis required.
Chickenpox Direct Contact & Airborne Given to those unvaccinated that did not have chickenpox.
Shingles Direct Contact Vaccine can still be given if you have had shingles.
Pneumonia Airborne Two vaccines given separately. All 65+ or immunocompromised should receive both.
Influenza Airborne Vaccine components change annually.
Meningitis Airborne & Direct Contact Given to anyone unvaccinated or at an increased risk, especially students.
Polio Food & Water Considered a routine vaccination for most travel itineraries. Single adult booster recommended.

Sources: CDC, WHO and ISTM

Many of the countries surrounding South Africa require proof of yellow fever vaccination for entry. Consult with a travel health specialist to learn if you will need the vaccine.

Malaria is present in some regions of South Africa. Use mosquito repellents, netting and antimalarials if you are traveling to these areas.

Medical facilities are common and in good condition in urban areas and near game parks. But, facilities are limited in rural areas. Most facilities only accept cash payments before a procedure is done. Medicare does not cover these expenses.

Visit our vaccinations page to learn more. Travel safely with Passport Health and schedule your appointment today by calling or book online now.

A visa is not required for US citizens visiting for less than 90 days. You will still need a valid passport and possibly proof of yellow fever immunization.

South Africa Entry Requirements

Do I Need A… For My Trip to South Africa?
Passport table check mark
Tourist Visa
Business Visa
Vaccinations table check mark

Sources: Embassy of South Africa and U.S. State Department

If traveling from a country that has yellow fever, you must have proof of immunization.

Due to its size, the climate of South Africa is different depending on the region.

The Southwestern corner of South Africa has a Mediterranean climate.

The interior of South Africa has a temperate climate.

The Northeastern part of South Africa has a subtropical climate.

A small part of the northwest has a desert climate.

Although there is a range of different climates in South Africa, temperatures stay in the high-90’s in summer and low-30’s in winter.

The majority of the country experiences warm days and cool nights. There is a rainy season from November to March.

Stay away from strikes and political demonstrations for they may often turn violent.

You should be extremely cautious of petty crime including theft and muggings in central business districts, especially at night.

There is some risk of animal attack at game reserves. If visiting one in South Africa, do not exit your vehicle.

Do not swim alone or at isolated beaches, for riptides can be sudden and dangerous. Be mindful of sharks.

Avoid an Embarrassing Stop

Diarrhea can easily ruin a trip.Over 70% of travelers
will have diarrhea.

Get protected with Passport Health’s
travelers’ diarrhea kit
!

Although many tourists come to South Africa to experience safaris and wildlife, South African wineries are not to be missed.

The best area to experience the wine culture of South Africa is called the Boland.

Towns in this area include Paarl, Stellenbosch, Franschhoek, Wellington and Tulbagh. Among these towns, some of the most popular wineries to visit include KWV, Diemersfontein Wine Farm, and Spier.

The best time of year to visit the Boland region is during April. During this time, wildflowers bloom on the mountainsides.

This area is also perfect for photographers and nature-lovers for its picturesque views.

Here are some essential items to consider for your trip to South Africa:

  • Bug Spray — Although the risk of malaria is relatively low, it is a wise idea to bring insect repellent.
  • Sunscreen and Hat — The sun can get hot, especially in the summer months. Protect your skin.
  • Light-Colored and Lightweight Clothing — Light clothing wards off wild animals such as mosquitoes.
  • Fleece or Jacket for the Night-Time – Although it may be hot during the day, South Africa can reach below freezing at night.

All Americans visiting South Africa should register online with the U.S. Department of State before departure. This will inform the office of your travel plans within the country and will allow them to reach out in the case of an emergency or evacuation.

Once in South Africa, the information for the U.S. Consulate is:

U.S. Consulate General Johannesburg
1 Sandton Drive (opposite Sandton City Mall)
Johannesburg 2196
South Africa
Telephone:+(27)(11) 290-3000 / 011-290-3000 (from within South Africa)
Emergency After-Hours Telephone:+(27) 79-111-1684 / 079-111-1684 (from within South Africa)
Fax: +(27)(11) 884-0396 / 011-884-0396 (from within South Africa)
Email: consularjohannesburg@state.gov

If you have any questions about traveling to South Africa or are wondering what shots you may need for your trip, schedule an appointment with your local Passport Health travel medicine clinic. Call us at or book online now and protect yourself today.

Customer Reviews

Passport Health – Travel Vaccines for South Africa

Overall rating: 5 stars – 15 reviews
★★★★★
“great experience“
“I had a great experience at passport health. I am going to South Africa an am a little worried but I was able to speak my concerns and feel comfortable by the expertise of the staff. He was friendly and very helpful with all of the questions I had.”

Submitted by: Marquesha
★★★★★
“Great place when immunizations are needed for travel“
“I feel confident that the nurse that I met with was knowledgeable about what was needed for my upcoming trip to South Africa. I would definitely use this clinic again!”

Submitted by: Sandy
★★★★★
“Great Clinic“
“The nurse was very knowledgeable regarding South Africa. Information book is very helpful.”

Submitted by: Frank
★★★★★
“nice surprise“
“After recently going through frustrations with another agency for a trip to South AFrica and waiting for their response as I prepared for this trip, I am very impressed with the efficiency and friendliness of the Passport health office!”

Submitted by: Jacque
★★★★★
“Excellent experience“
“I had a great experience at Passport Health in August 2015. I was preparing for a trip to South Africa. The nurse was knowledgeable about the immunizations I needed to travel there, and explained everything clearly. This is the second trip for which I have used Passport Health, and I will use it again next time!”

Submitted by: Catherine
★★★★★
“Very impressive and knowledgeable“
“From the moment I walked in the door, I was greeted by an experienced RN who welcomed me. She had prepared a professionally-bound informational packet that pertained to my upcoming trip to South Africa. It summarized the recommended vaccinations and precautions. She promptly called in my prescriptions to my pharmacy and gave pragmatic advice about dietary precautions, sunscreen recommendations, and insect repellents. I was very impressed with her knowledge and attention to detail. i would highly recommend Passport Heath to others.”

Submitted by: Jeanean
★★★★★
“Really knowledgeable and friendly“
“I recently went to Passport Health in Colorado Springs and received really good service. They recommended what vaccines I should get before taking a trip to South Africa next Saturday. They also gave me a packet with helpful information for my trip. Overall, I am glad that I chose Passport Health for my Vaccination needs.”

Submitted by: Russell
★★★★★
“South Africa trip“
“Had a very informative visit with the nurse. She gave us great information about our South Africa trip.”

Submitted by: Henry
★★★★★
“Very Informative!“
“I got all my questions answered about my son’s trip to South Africa. Our clinic experience was great!”

Submitted by: Chrisy
★★★★★
“Fantastic Job!“
“Best Clinic Ever – love the nurse who gave me my shots and set me up to travel to South Africa!”

Submitted by: Mary
★★★★★
“Excellent care“
“I have a trip planned to South Africa coming up. After getting conflicting and confusing information from various sources, I found Passport Health. I received definitive, thorough and helpful info and very fine care in delivery of the immunizations.”

Submitted by: Paul
★★★★★
“great experience!“
“The nurse was very thorough in explaining what vaccines are needed when traveling to South Africa.”

Submitted by: Sarah
★★★★★
“Great Service!“
“I never knew there were such places but was advised to seek out a specialty travel clinic to take care of everything we would need for a South Africa trip. Passport Health prepared a booklet for us with pertinent info on all of the places we would visit & advised on what was required as well as what was recommended. Convenient locations and on time appointments. Good service!”

Submitted by: Lorraine
★★★★★
“Excellent Staff and Facility“
“I had an appointment yesterday to prepare for my upcoming trip to South Africa and Zimbabwe. Your staff did an excellent job and your facility was very clean and well organized. Stephanie did a superb job explaining everything and discussing my options. I felt very comfortable with her and appreciated her professionalism. My trip to Africa will be a once-in-a-lifetime adventure and I am confident that with your help and care, it will be that much better.”

Submitted by: Alan
★★★★★
“Excellent Time“
“The staff was wonderful! She gave me a detailed report with the recommendations for my upcoming trip to South Africa, and spend a lot of time with me answering all my questions. Thank you!”

Submitted by: Cassy

On This Page:
Do I Need Vaccines for South Africa?
Do I Need a Visa or Passport for South Africa?
What is the Climate Like in South Africa?
Is It Safe to Travel to South Africa?
Wine in South Africa
What Should I Take To South Africa?
U.S. Consulate in South Africa

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