Heroes are cool, but it’s really easy to rally around a good villain.

The Lex Luthors. The Hans Grubers. The Lord Voldemorts.

It’s much harder to pinpoint the bad guy when it comes to disease.

While germs and bacteria make up the illness, they don’t provide a visible target to resent.

No, the blame and contempt for an epidemic often falls on “patient zero”.

This is how we get legends like Typhoid Mary. Vilified for carrying the deadly disease throughout New York, even though she had no idea what her actions could create.

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Imagine a plague that infected millions in just a year, killing as many as 5,000 people per day. For the Eastern Roman (Byzantine) Empire, this nightmare was a reality. Beginning in about 541 CE, the Plague of Justinian swept through Europe, killing up to a quarter of the Eastern Mediterranean population and possibly as much as 10 percent of the world’s population.

What Was The Plague of Justinian?

Despite the catchy name, the Plague of Justinian was identified as the bubonic plague, otherwise known for its 14th Century cousin, “The Black Death.” The disease earned its name from Justinian, the ruler of the Byzantine Empire at the time. It also has a double meaning, as Justinian’s handling of the crisis was almost its own form of infection.

As farmers and other workers were dying by the thousands, Justinian was unable to complete many of the projects he had started and began to raise taxes and change the tax code.

Procopius, a scholar of the time, explained:

“When pestilence swept through the whole known world and notably the Roman Empire, wiping out most of the farming community and of necessity leaving a trail of desolation in its wake, Justinian showed no mercy towards the ruined freeholders. Even then, he did not refrain from demanding the annual tax, not only the amount at which he assessed each individual, but also the amount for which his deceased neighbors were liable.”

What Were the Symptoms of the Plague?

We don’t know the exact symptoms of the Plague of Justinian. The current symptoms for bubonic plague include:

• Fever
• Headache
• Chills
• Swollen or tender lymph nodes
• Abdominal pain
• Gangrene

Procopius described victims suffering from these and also other symptoms including:

• Delusions
• Nightmares
• Comas

He even said some would die almost immediately after the onset of symptoms. However, we don’t know how accurate his reporting was. Procopius said the plague was killing 10,000 people every day, but modern estimates put the daily death toll to closer to 5,000.

How and Where Did the Plague Spread?

Like the modern bubonic plague, scientists believe the Plague of Justinian spread through fleas. Studies indicate the plague may have originated in China or India and was then transported to the fertile valleys of Egypt through trade routes. In 541, the Egyptian port of Pelusium was the first city to document cases, and, by 542, cases were seen as far north as England.

Due to the nature of ancient records, we don’t know the full extent of the disease’s spread. We know the Mediterranean region was the hardest hit, but anecdotal evidence indicates some cases occurred in England, Germany and other northern regions.

What Effects Did the Plague Have?

Justinian wasn’t just a leader; he was also a conqueror. By 542, he had reconquered most of the Roman Empire’s previous domain and was hoping to solidify his rule. The plague made this all but impossible as farmers, soldiers and other key members of society fell ill and died from the disease.

By 568, Justinian’s empire began to crumble as the Lombards invaded Northern Italy, and, within a few generations, enemies were at the gates. Byzantium remained a power through 1453, but it would never be as large as it had been before the plague.

Could The Plague of Justinian Resurface?

Just as with many other ancient diseases, this question has been under investigation for years. A study conducted by Northern Arizona University found the Plague of Justinian came from a now extinct form of Y. pestis or bubonic plague. So in short, it is still around. But, we are unlikely to see anything like Justinian’s Plague or the Black Death in modern times.

“We’ve greatly improved hygiene since the times of the great pandemics,” said one researcher. “The other thing is we not have antibiotics, and plague is susceptible to every antibiotic.”

To learn more about bubonic plague, see the CDC portal. To learn more about other eradicated, or nearly eradicated diseases, see our polio and measles, mumps and rubella pages.

If you are planning a trip, especially one where you may come in contact with rodents, book an appointment at your local Passport Health by calling or booking online today.

What are your thoughts on this terrible plague? Let us know in the comments below, on Facebook or Twitter.

For those who frequently travel, taking a trek on your own offers a new level of foreign freedom.

This eliminates all discussions for where to eat, what sights to see and how to spend down time.

But, what you gain in freedom, you may give up in feeling safe during that solo international trip.

The stories are unfortunately far too common. Whether it’s in the form of assault, verbal abuse or some other violent act. There are many reports of independent travelers facing dangers around the world.

This is not to say that people should avoid traveling. Only that to ensure a safer trip, you might want to take some extra precautions.

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In recent years, a disease most commonly associated with history textbooks has been making the news in various regions throughout the world. The bubonic plague, or ‘Black Death’ as it may have been called in your history class, has killed individuals in North America and throughout the world at an increased rate from previous years.

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Brazil is taking a radical step forward in eliminating its dengue fever problem: releasing thousands of mosquitos. But, before you think that the country has lost its mind, know that these aren’t regular mosquitos. The British biotech firm Oxitec has genetically modified the bugs to prevent them from spreading the disease.

Oxitec’s plan is simple. The genetically modified strain is male only, and these mosquitoes will seek out a female mate. Their offspring inherit the genes that ensure they cannot spread dengue fever. These offspring die before reaching maturity. Perhaps even more interesting is that the strain contains a gene that leaves a florescent marker on the mosquito, so researchers can easily track the spread of the strain.

The hope is that enough mosquitos will find mates and be able to create enough dengue fever free offspring to reduce the number of cases throughout the country. As of now, Brazil is the international leader in dengue fever cases.

Trials have shown that the release of the dengue-free males into areas have greatly reduced the population of mosquitos and, in some cases, have even eliminated mosquitoes from the area.

Brazil is the first nation to allow the release of these genetically modified mosquitoes, but successful trials have been carried out in varying locations throughout the world. Brazilian officials are hoping to lower the number of dengue fever cases before the Olympics are held there in 2016. India is also currently working with Oxitec to produce a similar program.

No studies show what the long-term effects of these types of programs could be on ecosystems, but it is certain that they will help curtail dengue fever in the short term. There is also the exciting possibility of using this methodology to reduce the spread of malaria.

Dengue fever is a disease transmitted to humans by infected mosquitoes. It can be fatal if untreated, and it affects as many as 400 million people annually, according to CDC estimates.

For more information on dengue fever and what you can do to prevent it in your travels, contact a Passport Health Travel Specialist via our website or by calling 1-888-499-PASS (7277).