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The Amazing Story of How Malaria Gave Birth to Mauve

August 3, 2016 by Will Sowards Leave a Comment

The race for a cure to malaria, led to the invention of the mauve dye.

It would be fairly safe to assume that if given a mauve bridesmaid’s dress or mauve curtains, most modern women would be less than enthusiastic. For years, the color mauve’s reputation has been far from fashion-forward, maybe even backward? But this wasn’t always the case.

Mauve enjoyed time in the limelight during the 19th century when the first synthetic dye mauveine, later nicknamed “mauve,” was accidentally and serendipitously discovered during the search for a malaria cure.

Malaria 101

Malaria is a serious, potentially fatal mosquito-borne parasitic disease. It is characterized most by symptoms that resemble a severe flu, including high fever and chills.

Today, about 1, 500 cases are diagnosed annually in the United States. These cases arrive with travelers coming from countries with high malaria transmission rates. Transmission is highest in warm, tropical climates, and especially in areas south of the Sahara desert and in South Asia.

Though still a concern today, malaria problems are incomparable to during 19th century colonialism. As the British marched into more tropical territories, malaria became widespread among colonists. Trade brought the disease back to Europe were it spread quickly.

Though there was a treatment (quinine), availability was limited. The only known natural source of this compound were cinchona trees in South America. Extraction of this compound from these cinchona trees was costly. There was a huge need to synthesize a cheap and more accessible treatment for the growing number of malaria cases.

In the Hands of a Teenager

In 1856, professor August Wilhelm Hoffman at Royal College of Chemistry saw this need as a promising opportunity. The professor gave his young student, William Perkin, the task of coming up with a solution.

Hoffman thought he had the solution to another problem, as well. He wanted Perkin to use the coal waste in the streets, a constant nuisance during the Industrial Revolution, as the main ingredient.

The 18 year-old Perkin set to work in a makeshift laboratory. After trying a couple different compounds to no avail, Perkin began working with a compound called aniline, one of the main byproducts of the coal waste. Again, he found nothing, but this time he was stuck with a tube full of thick, black goop. As he tried to clean out his test tube, he found that it was dyed purple. In fact, everything that touched the goop was stained. Perkin realized that, while he hadn’t discovered a synthetic treatment for malaria, he had discovered the first synthetic dye!

An Unexpected Discovery

Perkin’s discovery of synthetic dye was a welcome alternative to the centuries old natural dyes. Natural dyes were expensive and often difficult to use. This new synthetic dye was more affordable and accessible.

Historically dye, and especially purple dye, was hard to come by and was mostly associated with royalty and wealth. Now, the “common man” was able to use it as well.

Mauve became a fashion fad. French fashion icon Empress Eugenie, wife of Napoleon III, loved the color and had several dresses made using Perkin’s dye. Mauve became one of the most fashionable and sought after colors in Victorian Britain. In fact, the fashion trend spread so quickly that it became known as the “mauve measles.”

The fashion fad didn’t last past the 20th century. But, Perkin’s synthetic dye discovery still had strong implications. We still use synthetic dyes today.

Perkins never discovered a new malaria cure. That didn’t happen until 1934 when a scientist at Bayer laboratories, developed chloroquine. The advancement in other antimalaria drugs helped decrease the number of cases in Europe and throughout the world.

Do you have more questions about malaria or are you traveling to a place where malaria transmission is high? Read more about malaria here. Feel free to contact a Passport Health travel health specialist by calling or book online now.

What do you think about this happy accident? Feel free to comment below or share this article on Facebook or via Twitter.

Written for Passport Health by Adrienne St. Clair

Filed Under: General Posts

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