To help ensure the best service for our clients, service at this location has been temporarily suspended.

With 270+ travel clinics in North America, Passport Health is your local leading provider of travel vaccinations and medications. Prepare your health for travel, visit us before you go.
Suite 117
Bluffton, SC 29910
Find directions to Passport Health Bluffton Travel Clinic >>
Passport Health Bluffton offers the following services at this location:
- Travel Medicine Services, including administering recommended/required immunizations such as yellow fever certifications, for all international destinations.
- Vaccine Credentialing Services
- General wellness vaccines for a healthy lifestyle, employment and school admission

Directions to Passport Health Bluffton Travel Clinic:
- Suite 117 is on the SECOND FLOOR of Building 100 which is the only two story building in Plantation Park facing the Shell Station.
- The Shell Station (and the Ultimate Carwash) will be on your right after you turn off of 278 from either direction. At the stop sign, you will be facing our building (#100) which is located directly in front of the Shell Station.
- Coming from US 278-E: If you reach the light at Simmonsville Road you have gone too far. Turn around and follow the directions from US-278 W below.
- Coming from US 278-W/Fording Island Road: Look for the Shell Station (and the Ultimate Carwash) and the Dairy Queen on your left just after you go through the light at Simmonsville Road. Plantation Park is located between these two establishments.
Take Exit 8 and follow signs for Hilton Head/US-278 East. Continue to follow 278-E for about 12 miles. Turn right onto Plantation Park Way into Plantation Park. At the stop sign look straight ahead at the two-story white building – this is Building 100 and is the only two story building in this complex. You can see our office on the second floor to your right in Suite 117 (second office from the end). Turn right at the stop sign onto Plantation Park Drive. Take the first left into parking area which is 29 Plantation Park Drive. The clinic is located on the SECOND FLOOR facing the Shell Station in Suite 117. The elevator is located in the middle of Building 100 on the first floor. *Always use the Shell Station as your visual reference point and you cannot miss our clinic on the SECOND FLOOR in Suite 117.
Continue on US-278 W and go through the light at Simmonsville Road. Take the first left onto Plantation Park Way into Plantation Park. At the stop sign look straight ahead at the two story white building which is Building 100 and is the only two story building in this complex. You can see our office on the second floor to your right in Suite 117 (second office from the end). Turn right at the stop sign onto Plantation Park Drive. Take the first left into parking area which is 29 Plantation Park Drive. The clinic is located on the SECOND FLOOR facing the Shell Station in Suite 117. The elevator is in the middle of Building 100 on the first floor. *Always use the Shell Station as your visual reference point and you cannot miss our clinic on the SECOND FLOOR in Suite 117.
Customer Reviews
“I initially went to Passport Health fora Hep A vaccination and prescription for Malaria pills & Travelers Diarrhea. Spoke to Tara about the Yellow Fever vaccination and she suggested I think about it. Went back today for this vaccination and as before Tara was extremely helpful and so pleasant! Highly recommend this office!”
“This was the fastest clinic experience that I have ever had! I completed my vaccination records prior to cominng, so everything went smoothly. The woman was friendly, and I was done within 15-20 minutes of my arrival.”
“Excellent resource for travel health. Easy to schedule and well informed staff. Will use again.”
“Tara gave me so much useful info and tips for my upcoming trip to the DRC. She was knowledgeable, kind and genuinely willing to provide me with everything I need to know.”
“Joanne gave a thorough explanation of signs and symptoms of yellow fever. Also, possible symptoms of the vaccination shot itself. Very satisfied with her professionalism.”
“Overall this was a very good way to prepare for travel. The nurse was informative and very pleasant. She never did tell me her name, however. Other than that, she was efficient and knowledgeable. I got what I needed and am ready to go.”
“Lynn was exceptional and answered all our questions about out trip to South America. She made us feel more comfortable about what shots were needed and gave us valuable advice about exploring and security.”